Jane Richardson
Jane Richardson started out in math, physics & astronomy and received her B.A. from Swarthmore in philosophy. In 1964, she took a technician position in the lab where her husband Dave had begun as a graduate student in protein crystallography 2 years prior. Their structures of Staph nuclease at MIT (1sns) and Cu, Zn superoxide dismutase at Duke (2sod) were two of about the first twenty protein structures solved at the time. Jane and her husband then detoured into structural bioinformatics, ribbon drawings (which she developed to help classify recurring structural motifs in proteins), protein design, molecular graphics, and all-atom contacts for several decades, before returning to crystallography with a focus on improving the accuracy of protein & RNA structures.
The following tutorials are available to help new users learn to use MolProbity.
During her talk, linked here, Jane provided the following Zen advice on how to reconcile model anomalies:
The Zen of Model Anomalies:
Correct Most of them.
Treasure the meaningful, valid few.
Live serenely with the rest!
Acknowledgements
This venture would not be possible without generous funding from the ACA. We are grateful for the financial support. In addition, we would like to thank James Holton for continuing to provide logistical support. We are also indebted to our speakers for their time sharing experience and advice. Finally, thank you to Ms. Alyssa Crick for graphic design.
